2. Metabolic Disease

Metabolic Disease

Metabolic Disease

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Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W756134
    Chenodeoxycholic acid 24-acyl-β-D-glucuronide-d5 sodium
    Chenodeoxycholic acid 24-acyl-β-D-glucuronide-d5 sodium is the deuterium labeled Chenodeoxycholic acid 24-acyl-β-D-glucuronide sodium. Chenodeoxycholic acid 24-acyl-β-D-glucuronide sodium is a metabolite of Chenodeoxycholic Acid (HY-76847).
    Chenodeoxycholic acid 24-acyl-β-D-glucuronide-d5 sodium
  • HY-W756596
    1,2-Dioctanoyl-3-chloropropanediol-d5 2714417-65-7
    1,2-Dioctanoyl-3-chloropropanediol-d5 is deuterium labeled 1,2-Dioctanoyl-3-chloropropanediol. 1,2-Dioctanoyl-3-chloropropanediol (3-Chloropropane-1,2-diyl dioctanoate) is an ester product.
    1,2-Dioctanoyl-3-chloropropanediol-d5
  • HY-W762019
    1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin 39227-28-6
    1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin is a polychlorinated dibenzo-p-dioxin (PCDD) congener. 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin can cause pale (fatty) livers, gastrointestinal hemorrhage and early death in H/W and line A rats at the highest dose (10,000 μg/kg). 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin also induces sinusoidal distension, and even severe peliosis in line B.
    1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin
  • HY-W766801
    rac-1-Linoleoyl-3-chloropropanediol-d5 2489621-72-7
    rac-1-Linoleoyl-3-chloropropanediol-d5 is deuterium labeled 1-Linoleoyl-3-chloropropanediolte. 1-Linoleoyl-3-chloropropanediolte (3-Chloro-2-hydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate) is an ester product.
    rac-1-Linoleoyl-3-chloropropanediol-d5
  • HY-W774970
    Ethyl heneicosanoate 28898-67-1
    Ethyl heneicosanoate (Heneicosanoic acid-ethyl ester) is an ester product.
    Ethyl heneicosanoate
  • HY-W774974
    Methyl 16-methylheptadecanoat 5129-61-3
    Methyl 16-methylheptadecanoat (16-Methylheptadecanoic acid-methyl ester) is an ester product.
    Methyl 16-methylheptadecanoat
  • HY-W777050
    1-Palmitoyl-2-oleoyl-3-chloropropanediol 1363153-60-9
    1-Palmitoyl-2-oleoyl-3-chloropropanediol is an ester product.
    1-Palmitoyl-2-oleoyl-3-chloropropanediol
  • HY-W777649
    Oxypurinol-13C,15N2-1 1217036-71-9
    Oxypurinol-13C,15N2-1 (Oxipurinol-13C,15N2-1) is 15N and 13C labeled Oxypurinol (HY-19657). Oxipurinol, the major active metabolite of Allopurinoll (HY-B0219), is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout.
    Oxypurinol-13C,15N2-1
  • HY-W777865
    1-Linoleoyl-3-chloropropanediolte 74875-98-2
    1-Linoleoyl-3-chloropropanediolte (3-Chloro-2-hydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate) is an ester product.
    1-Linoleoyl-3-chloropropanediolte
  • HY-W777869
    1,2-Dilinolenoyl-3-chloropropanediol 74875-97-1
    1,2-Dilinolenoyl-3-chloropropanediol is an ester product.
    1,2-Dilinolenoyl-3-chloropropanediol
  • HY-W777872
    1-Palmitoyl-2-linolenoyl-3-chloropropanediol 1246833-14-6
    1-Palmitoyl-2-linolenoyl-3-chloropropanediol is an ester product.
    1-Palmitoyl-2-linolenoyl-3-chloropropanediol
  • HY-W777893
    1-Oleoyl-2-linoleoyl-3-chloropropanediol 1336935-03-5
    1-Oleoyl-2-linoleoyl-3-chloropropanediol is an ester product.
    1-Oleoyl-2-linoleoyl-3-chloropropanediol
  • HY-W777894
    1-Linoleoyl-2-linolenoyl-3-chloropropanediol 1612870-93-5
    1-Linoleoyl-2-linolenoyl-3-chloropropanediol is an ester product.
    1-Linoleoyl-2-linolenoyl-3-chloropropanediol
  • HY-W778187
    rac 2-Oleoyl-3-chloropropanediol-d5,95% 1331669-45-4
    rac 2-Oleoyl-3-chloropropanediol-d5,95% is deuterium labeled 2-Oleoyl-3-chloropropanediol. 2-Oleoyl-3-chloropropanediol is an ester product.
    rac 2-Oleoyl-3-chloropropanediol-d5,95%
  • HY-W778188
    2-Linolenoyl-3-chloropropanediol 1470071-08-9
    2-Linolenoyl-3-chloropropanediol is an ester product.
    2-Linolenoyl-3-chloropropanediol
  • HY-W778471
    rac-1-Linoleoyl-3-linolenoyl-propanetriol 126374-41-2
    1-Linoleoyl-3-α-linolenoyl-rac-glycerol is a diacylglycerol that contains linoleic acid (HY-N0729) at the sn-1 position and α-linolenic acid (HY-N0728) at the sn-3 position. It has been found in olive oil subjected to lipase-catalyzed glycerolysis with immobilized lipase B from C. antarctica.
    rac-1-Linoleoyl-3-linolenoyl-propanetriol
  • HY-W779019
    Xylose-13C5 1262683-58-8
    Xylose-13C5 (D-(+)-Xylose-13C5) is 13C labeled Xylose. Xylose (D-(+)-Xylose) is a natural pentose sugar that is catalyzed by xylose isomerase to form xylulose, which is a key step in the anaerobic ethanol fermentation of Xylose. Xylose can be used by microorganisms to produce fuels, chemicals, and bulk industrial enzymes. Xylose provides the substances and energy for cells, as a carbon source for the biosynthesis of high-value chemicals and biofuel. Xylose can be used to fully explore lignocellulose resources and provide a new direction for microbia fermentation.
    Xylose-13C5
  • HY-W779021
    Adenosine-15N 41547-82-4
    Adenosine-15N (Adenine riboside-15N) is 15N labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
    Adenosine-15N
  • HY-W779575
    cis-9,10-Epoxystearic acid methyl ester 2566-91-8
    cis-9,10-Epoxystearic acid methyl ester is an ester product.
    cis-9,10-Epoxystearic acid methyl ester
  • HY-W780142
    7-Hydroxy-3-oxo-Cholest-4-en-26-oic acid 115538-85-7
    7-Hydroxy-3-oxo-Cholest-4-en-26-oic acid is an ester product.
    7-Hydroxy-3-oxo-Cholest-4-en-26-oic acid
Cat. No. Product Name / Synonyms Application Reactivity